Vol. 7, Issue 10, Part B (2025)

The periparturient period in dairy cows is marked by significant physiological stress that often results in metabolic imbalances and increased disease incidence. This study aimed to evaluate the baseline hematological, biochemical, mineral, and energy-related metabolic parameters in crossbred cows during the periparturient period in Bathinda district, Punjab. A total of 32 crossbred cows from three different farms were sampled at three critical phases: Far-Off Dry (FOD), Close-Up Dry (CUD), and Fresh period (3–30 days post-calving) for various metabolic and energy parameters. Results showed a significant decline in Hb, PCV, and glucose levels postpartum, with the lowest values observed in farm no. 3, indicating higher metabolic stress. Elevations in BHBA and NEFA in farms 1 and 3 further suggested negative energy balance during early lactation. Among minerals, calcium and sodium levels declined significantly postpartum, particularly in farm no. 2, suggestive of subclinical hypocalcemia. Inter-farm differences highlighted varying management and nutritional strategies. The findings emphasize the importance of targeted monitoring and nutritional interventions during the transition period to enhance the productivity and health of dairy cows.