Vol. 6, Issue 1, Part C (2024)

This study is focused on the connection between an overly enhanced thyroid function, especially thyroid-stimulating hormone (TSH), and being overweight in youngsters and teenagers. The researchers also assessed the levels of leptin hormone and lipid profiles in obese individuals compared to non-obese individuals. The study included 100 participants aged 7 to 15 years, divided into two groups: So, I am going to assign 50 obese and 50 non-obese individuals as a control group and the body mass index (BMI) will be used as a rule for obesity. Blood was taken from the two groups in order to measure the levels of serum leptin, TSH, total cholesterol, triacylglycerol, cholesterol high density (HDL) and low density cholesterol (LDL) respectively. The statistical examination of this data was executed using the Statistical Package for the Social Sciences (SPSS), to find out if there was any significant difference between the two groups. The members in the obese group demonstrated a substantive hike (p<0.01) in their serum leptin levels as compared to the members in the non-obese group. On the other hand, the group with the non-obese showed higher levels of T₄, T₃, and TSH with lower levels of leptin and all samples of lipid profiles. Obese group was less secretory than normal temperament, for T₃ and T₄ and more secretory than non-obese for TSH, as well as revealed significant differences in lipid profiles. These results can therefore be interpreted that there exists some relationship between thyroid malfunctioning, leptin hormone levels as well as lipid profiles among obese kids and youth. Nevertheless, one has to acknowledge that though the article presents the general ideas on how there is the connection between those relationships and the causality, it does not provide the exact mechanisms behind that connection. Clearly, this needs additional research to shed light on possible beneficial results and possible therapeutic exposures.