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International Journal of Biology Sciences

Vol. 6, Issue 1, Part B (2024)

Serum kreb von den lungen-6 (KL-6) as a useful biomarker for evaluation of Covid-19 disease severity

Author(s):

Wafaa Fadhil Hamad

Abstract:

Aim: The study aimed to investigate the role of KL-6 in severe and non severe Covid-19 patients.
Method: In our study, 160 patients with Covid-19 were enrolled after being confirmed by RT-PCR. Estimation of KL-6, C-reactive protein (CRP) and lactate dehydrogenase (LDH) were performed, with comparing their levels in severe and non-severe cases. Study of the relationship between KL-6 and inflammatory marker was carried out by using the Spearman correlations.
Results: The results showed an increase in CRP, LDH & Kl-6 levels in the sera of Covid-19 patients, and highly significant increases were observed in their levels in severe patients than in non-severe cases (p= 0.001, p= 0.000 & p= 0.000), respectively. Spearman’s correlation showed significant correlation between KL-6 & inflammation. 
Conclusion: It can be concluded that KL-6 seems to be a useful biomarker in the prognosis of Covid-19.
 

Pages: 120-123  |  122 Views  38 Downloads

How to cite this article:
Wafaa Fadhil Hamad. Serum kreb von den lungen-6 (KL-6) as a useful biomarker for evaluation of Covid-19 disease severity. Int. J. Biol. Sci. 2024;6(1):120-123. DOI: 10.33545/26649926.2024.v6.i1b.197
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