Vol. 6, Issue 1, Part A (2024)

High-sensitivity C-reactive protein (hs - CRP), an acute-phase reactant produced by hepatocytes in response to inflammatory cytokines, has gained substantial attention as a prognostic biomarker for predicting postoperative complications. This paper evaluates the utility of hs - CRP levels in the early detection of infections, wound healing disturbances, and other systemic complications following surgical procedures. By synthesizing data from multiple clinical trials, meta-analyses, and hospital-based cohort studies, this paper establishes the correlation between elevated postoperative hs - CRP levels and patient outcomes across general surgery, cardiovascular surgery, and orthopedic interventions. Our findings reinforce the clinical relevance of hs - CRP in postoperative surveillance and its potential integration into routine surgical care pathways.