Contact: +91-9711224068
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
International Journal of Biology Sciences

Vol. 6, Issue 1, Part A (2024)

Impact of Toxoplasma gondii on prostaglandin, progesterone, oxytocin and anti-müllerian in abortion women

Author(s):

Nada AbdulSalam Mazael and Ohood Mozahim Shakir

Abstract:

The current study aimed to reveal the level of effect of the Toxoplasma gondii parasite on some sexual and nervous hormones and antioxidants. The current study was conducted in the city of Mosul and included 150 blood samples collected during the time period from March 2023 to November 2023 randomly from aborted women arriving at government hospitals and clinics. For age groups from 20 to 35 years, which is the ideal period for pregnancy and childbirth. Blood samples were collected from Women's Health Hospital, Doctors without Borders Hospital, Al-Khansa General Hospital, outpatient clinics, and some research laboratories. Blood samples were collected from aborted women suspected of being infected with the parasite, and then the samples were stored at 20 degrees. Until an ELISA test is performed to detect infection and estimate the concentration of specific antibodies, the samples are divided into the control group, which consists of 60 samples from non-infected women. Infected women, and the patient group, which consists of 90 samples from aborted women suspected of being infected with the parasite, where the infection was diagnosed by detecting specialized antibodies (IgG, IgM). Parasite. Two types of serological tests were used in the current study for the purpose of detecting infection: the ELISA-IgG test and the ELISA-IgM test. The results of these tests showed the presence of infection in women, which amounted to (1.176±0.591 pg/ml) and IgM (0.776±0.175 pg/ml). ml) inspector.
The results of the current study showed a significant increase p≥ 0.001 in the levels of prostaglandins and oxytocin in the group infected with toxoplasmosis compared to the control group, reaching (pg/ml 1508±243) and (pg/ml 644±205), respectively, with a significant decrease in p≥ 0.001 in progesterone levels compared to the control group, which amounted to (3.08±1.59 pg/ml). On the other hand, there was a significant increase (p>0.05) in AMH levels, which amounted to (9293±8324 pg/ml) compared to the control group.
 

Pages: 45-49  |  71 Views  21 Downloads

How to cite this article:
Nada AbdulSalam Mazael and Ohood Mozahim Shakir. Impact of Toxoplasma gondii on prostaglandin, progesterone, oxytocin and anti-müllerian in abortion women. Int. J. Biol. Sci. 2024;6(1):45-49. DOI: 10.33545/26649926.2024.v6.i1a.186
International Journal of Biology Sciences

International Journal of Biology Sciences

Call for book chapter