Vol. 6, Issue 1, Part A (2024)

In the developing world, medicinal plants are used to cure a wide range of illnesses. Research on them may result in the development of innovative medications for the efficient treatment of a range of illnesses. For this investigation, we selected the two most widely utilized plant leaves Cymbopogon citrates and Ocimum tenuiflorum after screening them for phytochemical and antibacterial qualities. The agar well diffusion method was used to qualitatively assess the antibacterial activity test against specific Gram-negative bacteria on a solid medium. According to the study, secondary metabolites including tannins, flavonoids, saponins, glycosides, alkaloids, and steroids were abundantly available in both Cymbopogon citrate extracts and Ocimum tenuiflorum. Additionally, it was discovered that plant leaf extracts exhibited the greatest inhibition against Pseudomonas aeruginosa, Escherichia coli, Shigella flexineri, and Salmonella typhi, as well as antibacterial qualities for a variety of gram-negative bacterial strains.