Vol. 5, Issue 2, Part B (2023)

Helicteres isora, commonly known as the screw tree, is a significant medicinal plant native to South and Southeast Asia. It has been used in traditional medicine systems, particularly Ayurveda, for the treatment of a variety of ailments including diabetes, gastrointestinal disorders, skin diseases, and infections. The plant contains a variety of bioactive compounds, including flavonoids, phenolic acids, alkaloids, and cucurbitacins, contributing to its broad spectrum of therapeutic activities. The present paper aims to review the biological activities and functional role of H. isora in plant-based therapeutics. Emphasis is placed on its antioxidant, antimicrobial, anti-inflammatory, antidiabetic, hepatoprotective, and anticancer properties. Through in-vitro and in-vivo studies, the plant has shown remarkable potential in promoting human health, with future research focusing on its clinical applications and therapeutic formulations.