Vol. 4, Issue 1, Part C (2022)

The study was undertaken to evaluate the therapeutic efficacy of Escherichia coli LPS and Neem oil in 40 infectious repeat breeder cows. The animals were divided in 2 different groups viz. Group-I 20 and Group-II 20 treated with E. coli LPS @ 100 mcg/ml activity in 30 ml sterile PBS and neem oil @10 mcg/ml in 30 ml distilled water in intrauterine route, respectively. The diagnosis was confirmed by estimation of pH, PMN cell count, White Side Test and Spinnbarkeit test, which indicated 93.00% cows having alkaline pH, PMN cell count >5% and all cases positive for White Side Test. Recovery rate after treatment were found as 16 (80.00%) and 15 (75.00%), respectively. The conception rate was found as 14 (73.68%) and 12 (63.15%) in cows in Group-I and II, respectively. On conclusion, cows treated with E. coli LPS showed higher recovery rate.