Ganoderma lucidum provides multiple benefits to human in terms of nutrient and medicine. Antibacterial potentials of this medicinal mushroom were assessed by making use of well diffusion and drug dilution methods on MDR bacterial isolates. Results revealed that all five extracts produced effective zone of inhibition with best by methanol extract against Escherichia coli and Pseudomonas aeruginosa (19.3±0.4mm respectively) and also with 266±23.6 MBC. Ganoderma lucidum extracts could be considered as an effective antibacterial agent.
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