International Journal of Biology Sciences

International Journal of Biology Sciences


International Journal of Biology Sciences
Vol. 3, Issue 1 (2021)

Review of nutritional states of viruses


Mostafizur Rahman

The nutritional status of the host has long been associated with both severity and susceptibility to infectious disease. The accepted model system proposes that inadequate nutrition impairs the functioning of the immune system, thus resulting in increased susceptibility to infection. However, current work suggests that not only can the nutritional status of the host affect the immune response, but it can also affect the viral pathogen. In a mouse model, a benign strain of coxsackievirus B3 became virulent and caused myocarditis in selenium- and vitamin E-deficient mice. This change in pathogenicity was due to mutations in the viral genome, which changed an avirulent virus into a virulent one.
Pages : 21-24 | 28 Views | 7 Downloads